10        20        30        40        50        60        70        80        90       100       110       120                    
                           ....|....|....|....|....|....|....|....|....|....|....|....|....|....|....|....|....|....|....|....|....|....|....|....|
Saccharomyces cerevisiae   -----------------------------------------------------------------------------------------------MPKVILESHSKPTDSVFLQPWIKAL 
Kluyveromyces lactis       -----------------------------------------------------------------------------------------------MPNVVLSSRLTNNDSVFLQEWIKPS 
Candida albicans           --------------------------------------------------------------------------------MFRSVSLSSLIPFLIIVSIAMQRPENDVPMIMQSSWLVNE 
Candida dubliniensis       ----------------------------------------------------------------------------------------------------MQKSENDVPMIMQSSWLVNE 
Candida glabrata           -----------------------------------------------------------------------------------------------MPPFIPKSRSNAVESVYLHGWVRDM 
Debaryomyces hansenii      ----------------------------------------------------------------------------------------------------MNVN-IKYPLVLHDNWLLES 
Ashbya gossypii            -----------------------------------------------------------------------------------------------MPKVVLASRAHKADSIFLREWLVDA 
Lodderomyces elongisporus  MDEYSHKQLLSLYGHDVRKYIEAHEQLEAEFEELRIHDDFMILRNEADKRDYRQLVLRLDPKILELFALSGQSEDAAVGGKSKRNFIGIQGFSKVKDCTLTTRELESLVKKHDHSWLLKD 
Pichia guilliermondii      ----------------------------------------------------------------------------------------------------MYEPTYEWEIVLQTTWIQKA 
Pichia stipitis            ----------------------------------------------------------------------------------------------------MNYNNDKFPLVFLQSWLWES 

                                   130       140       150       160       170       180       190       200       210       220       230       240           
                           ....|....|....|....|....|....|....|....|....|....|....|....|....|....|....|....|....|....|....|....|....|....|....|....|
Saccharomyces cerevisiae   IE----DNSEHDQYHPSGHVIPSLTKQDLALPHMSPTILTNPCHFAKITKFYNVCD-YKVYASIRDSSHQILVEFSQE-CVSNFERT--------HNCRITSETTNCLMIIGDADLVYVT 
Kluyveromyces lactis       VRPYYLKNEKTKFWPEQRELVTDLLEHDIIESAFQTALNPAPQRFVRIVKFHRVND-YTVYATIRDSTALILCYFTVD-CVLDYETI--------NNDRITLNTLNTLFVIGNVTLQFWN 
Candida albicans           VIKSINSNGQ---------YINALIKKDFQ-PTVLP-----VSFILRILKFTATTDSKDITAVLADSTHKIFAIFLFFPAIVDFENK--------YHHRMTYNTRSCLIRIHKANLKFMD 
Candida dubliniensis       VIKSINSNGQ---------YINSLIKKDFQ-PTVLP-----VSFVLRILKFTATTDSKDITAVLADSTHKIFAIFLFSPAIVDFENK--------YHHRMTYNTRSSVIRIHKANLRFMD 
Candida glabrata           LL----ESKTSQNIA----VIPRVDPDEASIPLLSRRIYANRRHFVKITKFFQVHN-YSVYASVKDSQHQILSQFTPK-CVSEFESR--------NRSRITSDTVNTLFMIGDAKLGIMV 
Debaryomyces hansenii      ITGQINKNVK---------YTNSLIKKDFISPSSIS-----KTPILRILRFLKTTKSSDLTAILSDSTHTVIAIFPFDPAIINFEIR--------YKHRITYHTPNSLILIKQANLRFVN 
Ashbya gossypii            VVPALERSGACAPWAGVECFIPALPPATATLS-LEPTVIQNPKRFLRIVRFTRVHD-FAVCAVARDAGCCILVEFTPH-CVSNFERR--------YHQRITSSTVNSLFVIGNTSLLFYA 
Lodderomyces elongisporus  ILLLIKRHPR---------LMEPMINRKFKPNNGKS-----TPFYLRILEFGERSSNGAINVVMGDQTHKVCCIFPRKTVLRHMSRGKLMMGMFGLDNGFVAHAIYNFVLVKRARLRFEE 
Pichia guilliermondii      VTRCLQHHLR---------FSATDVEHHFIHPSHKKHVR--ETPIIRVYRYLKTTDQLALTAIVSDTRHLIFAKFPYDPTIIKFEQL--------YRQRLTYMTAGCLFVIKQAKLRFAK 
Pichia stipitis            VEKCIDPSRR---------YTSSLIKKNFVDETPRK-----ASPIVRISKFIKVTDNKDLTVILSDSTNLMFAIFPFKPTIVNFEDK--------YKQRITFHTQNILIHIKKANLRFIE 

                                   250       260       270       280       290       300       310       320       330       340               
                           ....|....|....|....|....|....|....|....|....|....|....|....|....|....|....|....|....|....|....|....|....|
Saccharomyces cerevisiae   NSRAMSHF----KICLSNISSKEIVPVLNVNQATIFDIDQVGSLSTFPFVYKYL--------------------------------------------------- 
Kluyveromyces lactis       HRECKLWFNQ-DFPGLR------MVPVLKIEKARMFDRDQISSNVQFEWVYDTLHG------------------------------------------------- 
Candida albicans           KSTVKKCYGR-KSDGGLAIAVLEVLEFDIFFKDQYSFINSIENRLKYVYDDVEYNQLCG---------KKKHKP----EYEDLMCDI------------------ 
Candida dubliniensis       QSTVNKCYNM-KTNGNLAIAVLEILEFDIFLKDQYSFITSIENRLKYVYEDTRYDQLCR---------EKMHRP----EYDDLMCDM------------------ 
Candida glabrata           VDELRHYFGE-KIVSLFNGLDMPYIPYLIINQAFILDYDQVEAFKMTPFVYQYI--------------------------------------------------- 
Debaryomyces hansenii      NVELTTEWGI-TIEDEIDVAVLEVLDLEIFQRDQIMLGVNIENNLQLIYYDKSYLNLCGKSRQRDSLGEKEIKEVISQSYDDVVSI------------------- 
Ashbya gossypii            RSDAAAAF---EVPALMNGSS--TLPVLRVGDCAIFDQDQVESHRRFPLVQEHPRFVQSLDMAMQGSVLSRYT-------------------------------- 
Lodderomyces elongisporus  RSYIRDHFNLPKISSKLKYCVIEILDFEYVASVKAALQRKLPNFCSKDVKQNYNKALENAKQTDLESDEEFEADEEPLPDAELDFNKHDCKYVYNIDLYVRYCRQ 
Pichia guilliermondii      PGEVAKDFDF-SISPNIQIVILEIDDFTVFSRDQAILPHEALSKVNMIYYDREYYDLCGRDCYIPEYSKDVEKQVS-DDYGDVVSV------------------- 
Pichia stipitis            RKDYP-LYEI-PAMG-LSMVVLEVLDLEIFQRDQIMLSNKVESTLKFLHNESNYESLFG--RKWNNAEENNDRE----DYDDVVSF-------------------